The Notts County boss admits he's enjoyed some good results against City.
"I had some good times with United against City and we only lost once, that was my second game for the club," said Ince.
"I remember we beat Millwall 5-0 at home in my first game and I thought it was easy, then we went to Maine Road and got beat 5-1.
"It was probably one of the worst days of my life, and I never want to feel like that again. I couldn't leave my hotel room in Manchester for a few days. That was the only time we got beat by City when I played.
"If we were to beat them I would get the same buzz I did when I beat them with United.
"It would be fantastic. First and foremost, we have got to go out and do ourselves proud."