Manchester United have been hit by a triple injury blow.

United could be without Robin van Persie, Shinji Kagawa and Patrice Evra for their Barclays Premier League game against Wigan at Old Trafford on Saturday, says the Daily Mail.

Van Persie was taken off with a thigh problem during Holland's win over Hungary on Tuesday while Kagawa sat out Japan's game with Iraq with a back strain.

And left back Evra was so poor in France's World Cup qualifying win over Belarus that he may be rested ahead of next Wednesday's Champions League opener at home to Galatasaray.