With Sir Alex Ferguson having brought Dimitar Berbatov into his first XI to replace hamstring victim Wayne Rooney, the United manager then lost Jonny Evans to injury in the warm-up and had to call in Antonio Valencia.
Ferguson said: "It is not easy. With Hernandez he gives you that penetration and speed. That was a loss.
"Jonny thought he would be okay but in the warm-up it was no use. We had to make that change."