After having their lead cut to two points on Saturday, United could open it up to eight again when they entertain Everton next Sunday.
And that would set up a derby with City at the Etihad Stadium on April 30 when victory would see them crowned champions.
"I couldn't care less," defender Rio Ferdinand said about that prospect. "As long as we can win and we get the trophy, I couldn't care less where we win it.
"The fans would love it, but as long as you get your hands on the trophy you would take it in the back garden."
United manager Sir Alex Ferguson is not even prepared to go that far.
"You can never be too confident in this game," he said. "My experience tells me that there is always something that is going to bite you on the bum.
"Hopefully we can avoid that."