Jose Mourinho had previously suggested he did not fancy taking his Manchester United side on a trip to Russia in the last 16 of the Europa League.
His nightmare came true as FC Rostov were pulled out of the bag.
He said: "It is a bad draw in every aspect. Far and difficult. Comes in a bad period.
"They had a very good Champions League campaign. They beat Ajax and Anderlecht in qualifiers and managed important results against Bayern Munich and Atletico Madrid.
"They got third position in their group, leaving PSV Eindhoven out. I know the coach well. The team are very defensive and physical. It's a bad draw."