United host Chelsea tomorrow in the quarterfinals.
Ferguson said: "A big game is the best. We're at home and with a home draw in the FA Cup we'll play anyone.
"Chelsea have a terrific cup record themselves, the best in the last decade, and we haven't won it for nine years so there are a lot of incentives for us.
"Rio Ferdinand hasn't got a medal, for example, so that's another great incentive for us."