Fergie believes it would be a significant moment in his Old Trafford tenure if they were to come out on top.
"If we win [on Sunday] it will be one of our best ever results," Ferguson told MUTV. "They are a really good, powerful team with massive players.
"It won't be easy and if we defend like we did at Reading we'll be in trouble.
"The important thing for us is to take lessons from the mistakes we're making and do something about it. We need to find a solution."