Ferguson was happy at the way Van Persie and Kagawa combined in a thrilling first-half display.
"It was fine," he said.
"Obviously it is early doors and there will be a better understanding as time goes on."
And it seems Ferguson is intent on operating with someone occupying a deeper role behind Van Persie, suggesting Rooney will not be able to take his first-team place for granted.
"We normally do that, whether it is Wayne who plays in that role, or Danny Welbeck can do it," said Ferguson.