Welbeck got the nod to partner Wayne Rooney in the Barclays Premier League opener at West Bromwich Albion while Dimitar Berbatov, Michael Owen, Federico Macheda and Mame Biram Diouf are the other striking options.
"Rooney's been flying in pre-season," said the boss. "His fitness is terrific, he has that restless energy, he never stands still. He's a tremendous asset to our squad.
"It's interesting to see how he's combining with Welbeck at the moment - they've done very well together. Obviously when Chicharito comes back, I've got a selection problem because the boy's got goals written all over him. And there's also Berbatov, who's done very well in pre-season."