Greater Manchester Police were called to the hotel in the early hours of Tuesday following reports that a 26-year-old woman had been raped.
Northern Ireland international Jonny Evans, 19, was arrested and released on police bail. He has strenuously denied the allegation.
Ferguson is thought to feel his senior players should have been more aware of potential trouble which might accompany such a high-profile team outing, from which only Cristiano Ronaldo was missing.
However, as usual, Ferguson has opted not to enter any public debate about internal disciplinary sanctions or the merits of having a party in the first place.
"I have nothing to say about the events of the week," he said.
"Why would I say anything?
"Alex Ferguson has been dealing with situations like this for 21 years - and I know exactly what we do.
"I will not be guided or instructed by anyone. It is a club matter, and we will carry on the way we have always done."