The treble took Berbatov's goals tally for the season to 18, all but one of which have come in the Premier League.
"It was a marvellous performance from Dimitar," said Ferguson.
"He could have scored more. We were a bit wasteful with our finishing at times but you can't complain at the performance."
United won 5-0 and Ferguson added: "It certainly helps the goal difference, there is no question about that.
"We have some tough games ahead but hopefully the players can grasp the nettle.
"We have some experience. We have the squad. Hopefully we can manage all the games we have ahead."