Samaras has made just three appearances for Sven-Goran Eriksson's side this season and Lazio sports chief Walter Sabatini has already enquired about his availability.
"I can say that I feel good in England. But I must be honest, should Lazio show an interest towards me, I'd be really happy.
"They are a side with a big name. I know they play in UEFA Champions League and should they if they beat Olympiakos they will go to the last sixteen. I would be proud to play for one of the greatest European sides."
And Samaras has confirmed that Eriksson will not stand in his way of a move.
"At Man City I feel myself part of the team and I always hope to play. The coach told me that I'll have my chance, but that I must wait my moment.
"But he also said that should I want to leave, he wouldn't put obstacles in my way."