Kompany has been out of action after picking up a groin injury in the Champions League encounter against Real Madrid in May but there were suggestions that the defender could make a return to first team action during the Manchester derby on Saturday.
As it turned out, Kompany did not feature during the game and Guardiola has now gone on to reveal that although the Belgian international is close to full fitness, City are handling his situation with extra care due to his previous injury record.
"We cannot win titles and so on without all the players. So I'm looking forward to Vincent and Gundogan coming back, because we need them all," Guardiola said.
"I would prefer to come to Old Trafford with all of the key players, believe me. He has something in his muscle and we believe that was a problem for the many injuries.
"I think it's the last part of that because he's training with the group. And when I see him, I say 'wow - this guy can play' because he's training like Vincent is. But the doctor said with what happened in the past, we have to be careful."