The Sun says City hope to seal the signature of Van Persie by selling Adebayor to Tottenham for £5million.
Spurs, now prepared to deliver a massive U-turn and pay nearly all of Adebayor's £170,000-a-week wages, aim to do the deal this week.
City believe the transfer would be a major step towards landing Arsenal's skipper, as the Dutchman is not on speaking terms with the Togo star.
Van Persie, who insists he does not want to sign a new Emirates contract, is understood to be keen on a move to the Etihad. But City boss Roberto Mancini is aware there is no way Van Persie will go near the club if Adebayor remains.