Manchester City captain Vincent Kompany is struggling to make their clash with Chelsea.
The Daily Mail says the defender reportedly left the Etihad Stadium on crutches after suffering a knee injury in the second half of City's Champions League draw with Real Madrid.
The 26-year-old briefly left the field for treatment 10 minutes from time but played on until the end of the match.
Kompany received further treatment after the final whistle and was unable to conduct post-match interviews with the press.