Hughes said: "On the day I met him in London 10 days ago, one of the first things he said was that he can't wait for the game because he can't wait to play against Chelsea, so that's a good sign.
"The intention is that he plays a part on Saturday. The one impression everyone has of Robinho is that as soon as he gets the ball you sense something is going to happen and I think everyone will see that at the weekend.
"By all accounts he did not pick up any injuries [against Bolivia] last night and played 90 minutes, but like all the players who have been away on international duty we will have to get them back and have a look at them."
City's takeover by the Abu Dhabi United Group has shot the club into the same sort of spending stratosphere as Roman Abramovich's Chelsea, and Hughes said the fixtures computer could not have thrown up a better match to set pulse racing.
He said: "I know it's being billed as the 'clash of the cash'.
"We are really looking forward to getting back to playing football and the fixture against Chelsea is a fantastic one for us, it's the perfect game for us given the circumstances."