Lovren is available from Dinamo Zagreb for £7 million.
"Lovren is a quality player, but we are still negotiating," said Lacombe. "We heard in Zagreb that Chelsea and two Spanish clubs are interested in him.
"Chelsea are the club where he might want to go. We'll try another approach to the player but it is complicated at present.
"If he comes to Lyon, we believe he will fit in well because he reminds us a lot of Edmílson, a Brazilian footballer."