The 18-year-old striker moved to Griffin Park in early January but made just four substitute appearances for the high-flying Bees.
Boss Mark Warburton told the club website: "It was a pleasure to have Chuba at Brentford for his first loan spell away from his home club.
"He made an immediate impact both in training and in matches and I hope very much that he returns to Arsenal having benefitted from his experience with us.
"The difficult aspect was that he came to us at a time when the team was performing exceptionally well and as such, it was impossible to make unenforced changes.
"This meant Chuba did not perhaps get as many minutes on the pitch as he might have initially expected.
"I would like to thank everyone at Arsenal - particularly head of youth development Liam Brady - for working with us during Chuba's loan and everyone at Brentford wishes Chuba all the best for the future."
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