The Reds boss will field a second-string side in tomorrow night's Europa League opener against Swiss club Young Boys with him admitting that the domestic competition takes preference.
"I can understand why people would perceive us as not taking it seriously but I will always do what is in the best interests of the football club," said Rodgers.
"There is no doubt the Premier League is our number one priority, I've made that clear from the off with the position with our squad.
"If I lose some of my key players that can make it very difficult for us for the next two or three months.
"I am fully aware that when you pull on a Liverpool shirt you are expected to win the games so I've brought a team I believe can win the game."
Rodgers is likely to deploy the likes of Samed Yesil, Suso, Andre Wisdom, Conor Coady, Adam Morgan, Jack Robinson and Dani Pacheco in Liverpool's line-up after resting senior stars Steven Gerrard, Luis Suarez, Jose Reina, Glen Johnson, Martin Skrtel, Daniel Agger, Joe Allen and Martin Kelly.