The Spaniard has developed a good understanding with the 29-goal striker and provided another assist for the Barclays Premier League's leading scorer against Tottenham on Sunday.
"If you are good players you understand each other," said Enrique.
He added: "When I was at Villarreal with Forlan I linked up really well with him as well.
"In the game all the time the first person I look for is him (Suarez) and he always makes a movement and I try to put the ball there and he does the rest.
"It is really easy to understand with him. He is our best player and he can do something from nothing.
"It's like at Barcelona - the first player they look for when the game is in a bad situation is Messi because you know he can do something.
"Luis is the same - I look for him because I know he can do something different and we understand each other."