Ayre said Wisdom's new contract was indicative of the direction the club was moving.
"It's another great example of a player committing to the club and what we're trying to achieve under Brendan," he told liverpoolfc.com.
"He's a great young player, shown a fantastic improvement, broken into the first team and made a huge contribution and, rightly so, we've provided him with a new contract and a long-term one.
"Getting talent like him, Raheem and others to commit at this point is absolutely essential to the future.
"The manager, the owners and everyone have said the key is to build something for the long term and young players are a catalyst to that. None more so than Andre.
"He's come on leaps and bounds in the last year or so and that's because of all the hard work he's put in and the manager giving him a chance, so it's absolutely essential players like that commit themselves to the club."