The Reds must overturn a 2-0 deficit from the first-leg.
"The noise level is so important. There'll be 40,000 here and with the roar that can feel like 100,000 people," Rodgers told Liverpoolfc.com.
"That's the uniqueness of Anfield and the supporters - that's why this football club is renowned worldwide. We need that more than ever.
"The players on the pitch will do the supporters proud and I'm sure the supporters will all get together as one, and we can make it a really special occasion.
"The history of the club is based on great European nights. Of course we would rather have the game in a better situation but it should be really exciting for us."