Liverpool begin Capital One Cup defence against West Brom, Man Utd draw Newcastle
European champions Chelsea host recently-relegated opposition in the form of Wolves, who were the last side to book their place in the third round with victory over Northampton on Thursday night.
Andre Villas-Boas' Tottenham make the long trip to Brunton Park and Carlisle, while Everton cross the Pennines to take on Leeds.
QPR and Reading face off at Loftus Road and West Ham welcome Wigan in the two remaining all Premier League encounters.
Norwich are at home to Doncaster while Swansea travel to Crawley, and Swindon's reward for ousting Stoke is a home tie against Burnley.