Kuyt feels the Reds' summer transfer dealings make them an even stronger proposition this time around.
"I think we have more strength in the team now and definitely more depth," he told liverpoolfc.tv. "They have also added a couple of quality players - it will be interesting to see Raul Meireles again and everybody knows how good Mata can be.
"It will be an interesting game and we're all looking forward to the big games, we can't wait to play them, and hopefully we can get the three points."
Kuyt said: "We've played against Fernando already, and that's always strange. The first time is always the most difficult, but once you're on the pitch you want to do and you try to do everything to do that."