Wijnaldum has dismissed Everton's hopes of comparing with their city rivals because they don't compete for titles.
Everton find themselves 11th in the table and just seven points clear of the relegation zone.
"Yes of course, Manchester United are one of the biggest teams in England. The rivalry between us makes this game even better," Wijnaldum said at a Hugo Boss event on Thursday night.
But then he decided to throw barbs at the blue side of Liverpool.