The Reds enjoy a 2-1 lead from the first leg in Germany, but Klopp maintains that the tie is far from over and it would be a mistake to underestimate the Bundesliga side at Anfield.
"We worked hard for this goal last year and we've got a good result coming out of the first leg, as winning at Hoffenheim is no mean feat and I don't think there are that many teams that have won away at Hoffenheim.
"But if you think they will come into the game thinking they have nothing to lose, you have another think coming.
"You've seen how dangerous they are, we performed well in the first leg and we need to play very well tomorrow. Anything else that's covered in the media, that doesn't really matter. You need to focus that out."