After defeat to Chelsea, Tottenham boss Harry Redknapp confirmed Ledley King had suffered a hamstring injury.
King does not train in the week because of a long-standing knee problem and Redknapp said: "I've suddenly lost three of my best centre-halves.
"Ledley has done his hamstring. He's the most fantastic person and player, and he's so important for us, but if you don't train you can't just go out and play without doing hamstrings, groins or calves.
"(Sebastien) Bassong doesn't look too good, either. He got a bang on the head and his eye's all swollen up. It doesn't look too clever at all. I think the doctor has taken him to hospital with concussion.
"(Jonathan) Woodgate's nowhere near playing again. He went to see a specialist again yesterday and he just can't train.
"We haven't got to the bottom of the injury at all, what's causing him discomfort. (Michael) Dawson has a chance, he's the one.
"Jonathan had an operation last season and he's come back no better.
"The penalty decision, Ledley going off, they were the turning points. We defended abysmally for the second goal but we couldn't handle Drogba.
"I said to Kevin Bond as soon as Ledley went that I knew we couldn't handle him. He'd bully us. He was too strong."