The Spanish champions were held to a 1-1 draw by United in Madrid last month and despite that scoreline, Brazilian ace Kaka is positive about producing the required result at Old Trafford on Tuesday night.
"Every player wants to play a match like this," he told Real Madrid's official website.
"We came off the first leg in the Bernabeu with the feeling that we could have won the game and that we can equalise the draw in England and win.
"Manchester is really strong but we're going to Old Trafford with confidence. It's a traditionally European squad that always goes far in the competitions they play in. They also have really sold individual players like (Wayne) Rooney and (Robin) van Persie.
"The stadium is fantastic, just like the ambience and the fans."