He is expected to agree a bumper contract that would eclipse even Wayne Rooney's £220,000 a week.
A team-mate told The Sun: "Everyone expects Wesley's move to United to be announced soon, maybe as early as Wednesday."
Inter are resigned to cashing in on the 27-year-old Dutchman.
The source added: "He has even spoken to Dutch international team-mate Nigel de Jong to find out where are the best places to live in Manchester.
"It all looks imminent, no matter what Inter or Wesley may say in public.
"It seems Inter want to sell but don't want to admit it, while Wesley wants to go but doesn't want to say it. It's a good move for him and good business for Inter."