Inter go into the game on the back of victory over Fiorentina.
"Winning tomorrow would not mean anything in particular except to add three points to the League standings," said Ranieri.
"There is no turning point, you know what I think, we are continuing to work as we have always done and tomorrow night we need to do well against a team that knows how to play football, that has many new players, they know how to organise themselves and after seeing them against Siena I can only speak positively of Genoa.
"We must think only of ourselves, of our road, which is not free from incidents. We need to shut up and keep going."