Wenger's Gunners team will have their hands full trying to keep the Uruguayan international and his striker partners Leo Messi and Neymar quiet when the North London club faces the La Liga outfit in their Champions League Round of 16 clash on Tuesday.
"I used to think 'what if I signed Luis Suarez' before, but not now," Wenger said.
"Suarez is the kind of guy who manages to create that spirit in teams. Apart from the individual talent the three have, they also have a good understanding, cohesion and great solidarity.
"I have seen that Lionel Messi gave the ball to Suarez from a penalty, because he wanted him to be the best goal-scorer.
"When you see someone like Messi - who had the opportunity to score his 300th goal - do that, it means there's really something there.
"Individually, all their players are difficult to stop. We have to find a way to do it collectively. We have to analyse what we do and do it well and together. We have to keep Suarez quiet on Tuesday night."