The first clash between Manchester City and Manchester United this season will be overseen by the Premier League's leading official and the hot-favourite to be England's representative at the 2014 World Cup in Rio.
It is an eagerly anticipated affair, with new managers' David Moyes and Manuel Pellegrini set to face off the first time.
His last United game came in Sir Alex Ferguson's final defeat as manager, as Chelsea won 1-0 at Old Trafford, with Webb dismissing Brazilian full-back Rafael Da Silva following a wild kick at compatriot David Luiz.
City are unbeaten in their last eleven games in which Webb has been the man in the middle.
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