Laryea Kingston has suffered a recurrence of his hamstring injury and could be on the Hearts sidelines for up to seven weeks.
The problem flared up during Saturday's goalless Clydesdale Bank Premier League draw with Dundee United.
The 29 year old was jeered by his own supporters when he limped off towards the end of the game as Hearts had already used all of their substitutes.
Boss Csaba Laszlo told the Edinburgh Evening News: "Larry told me yesterday that he will be injured for the next six or seven weeks.
"I don't know if he will go away with Ghana, this is a decision for Ghana's football federation."