Guidolin was disappointed with the jeers during the 1-0 win.
"I was pleased to bring home a difficult and deserved victory, because we came up against a Genoa side that closed everything down," he told Sky Sport Italia.
"Despite the fact we didn't create that many chances, I was satisfied with the approach, the determination and the overall performance.
"It's better that the fans take it out on me. Perhaps some think we can win the Scudetto, but we've already performed miracles here.
"Something has changed in the atmosphere around the club. I made my decisions, but it looks as if the passion around me is ending, even though my passion for Udinese has only strengthened."