Giggs feels that Van Persie is capable of playing with any of the forwards at the club already.
"No matter what partnership the manager goes with up front, it looks mouth-watering," said Giggs.
"It's not just about the type of goals we know all the strikers can score, but the movement they have and their all-round play.
"Whoever the manager puts out there will do well, I'm sure. It's the manager's job to juggle all the players and pick the right systems for the right games.
"We all know that if you go on cup runs and Champions League runs, you need strength in depth in the squad because you're going to get injuries and suspensions and dips in form.
"So you need a big squad to compete at the top. They [Welbeck and Hernandez] are young lads and good lads who want to learn.
"They've already learnt a lot from Wayne and you've seen the improvement from both players. There's no doubt Danny and Chicha [Hernandez] will learn plenty from Robin."