"When you look at the quality Arsenal have, I don't think we can finish off their title hopes on Saturday," said Giggs.
"They have got a few players out at the moment - but all four top teams, if they are there or thereabouts, are capable of going on a run. That has always been the case.
"I expect us all to be involved at the end. We are going to have losses of form and not get the results we want. Hopefully we have had our poor spell."
However, as they collected 13 points out of a possible 18 against their major rivals last term, those setbacks mean there is a bit of catching up to do.
"We have to go there and try to win. We have not won at the Emirates Stadium, so it would be nice to do that."