But Giggs feels the way United adapted to the additional losses last night bodes well for the future.
"There was no disruption," said the veteran Welshman.
"The manager has chopped and changed this season already, whether that be due to injuries, or suspensions or whatever and we have coped with it, just as we coped with what happened in Kiev.
"It just proves the value of having a good squad.
"I think a few players are due to come back shortly and once that happens, we will start to look strong again."