Ruiz moved to Fulham in August from the Dutch club.
"I think they will play very offensive because when Twente plays at home, they normally do that," Ruiz told fulhamfc.com. "They will try to press us and try to keep the ball, that's one of the qualities Twente has.
"I think we can win the game but we have to be really focused, defend well and also keep the ball when we have it. I think for sure we'll have chances so we have to convert the chances we create.
"We have to take care of Nacer Chadli, Luuk De Jong and Ola John and also Emir Bajrami - if those players play they are very good. Twente are not having the best season but they are doing well in the Europa League, they know that they are through - but they will like to finish well.
"The Fulham supporters will help, when we have the supporters behind us we get extra motivation so, for sure it will help the players."