Les Bleus take on Finland and Belarus at the start of September and Deschamps is hoping the injury-prone Diaby can have a positive influence after returning to the fold at club level.
"Diaby has enormous potential. He had a disastrous season last year, but he has done a full pre-season and has played 90 minutes," Deschamps said.
"He is a very fragile player but he seems to be on the right track and I hope that nothing will hold him back now."
France squad for Finland and Belarus WC qualifiers
Mickael Landreau (Lille)
Hugo Lloris (Lyon)
Steve Mandanda (Marseille)
Gael Clichy (Manchester City)
Patrice Evra (Manchester United)
Christophe Jallet (Paris St Germain)
Laurent Koscielny (Arsenal)
Adil Rami (Valencia)
Anthony Reveillere (Lyon)
Mamadou Sakho (Paris St Germain)
Mapou Yanga-Mbiwa (Montpellier)