Fresh from scoring in Thursday's Europa League draw with Rapid Vienna, McDonald is chomping at the bit to score in the first Old Firm Derby of the season.
"It doesn't come any bigger than this in the SPL and we know we have a huge chance to extend our lead to seven points with a win at Ibrox," McDonald said today.
The Old Firm Derby is just one of several huge matches on Setanta this weekend, with some huge Bundesliga clashes as well as Serie A action with AC Milan desperate to return to the winners' circle away to Atalanta.
Friday 2nd October
8:10am Copa Sudamericana Lanus vs LDU Quito LIVE
Sunday 4th October
7am Ligue 1 St Etienne vs Bordeaux
8:45am Ligue 1 Lens vs Lyon
10:30am Bundesliga Monchengladbach vs Borussia Dortmund
12:15pm Eredivisie AZ vs NAC Breda
8:45pm Setanta Sports Cup Linfield vs Derry City
10:25 SPL Rangers vs Celtic LIVE
Monday 5th October
12:25am Bundesliga Stuttgart vs Werder Bremen LIVE
2:25am Bundesliga Hertha Berlin vs Hamburg LIVE
5:40am Serie A Palermo vs Juventus LIVE
8am Serie A Atalanta vs Milan
9:45am Russian Premier League Lokomotiv vs Rubin