FIFA president Sepp Blatter is pushing to have foreign quotas introduced to European leagues - including the Premiership.
He wants clubs to be limited to five foreigners in their starting XI to allow homegrown talent to flourish.
Premier League spokesman Dan Johnson told BBC Football Focus: "It's just not legal - under EU law we couldn't do it."
The 71-year-old Swiss argues that football deserves special treatment because it is not like any other job.
"Workers in Europe can circulate freely but footballers are not workers," he said.
"You cannot consider a footballer like any normal worker because you need 11 to play a match - and they are more artists than workers."
Blatter says he is ready to fight any EU move.
"Football has never had the courage to go against this practice," he said.
"When you have 11 foreigners in a team, this is not good for the development of football, for the education of young players, and there is a financial aspect, too."
But Johnson says clubs in England are ploughing money into their academies in order to produce homegrown players.
"We have to get it right organically," added Johnson. "It is a much better scenario to have quality youngsters coming through in all our clubs.