With Liverpool for six years up until 2012, the 36-year-old became a firm favourite at Anfield and netted a hat-trick in a 3-1 success over United in March 2011.
"I played there for six years and for me it was one of the biggest games of the season so now to play again against Manchester United is great," Kuyt said.
"It's a great chance, not only for me but for Feyenoord, for the team, we have a young team.
"It's good experience for them and a great game to play, so we're really looking forward to it.
"I have great memories of playing against United. We won a couple of games, I scored a hat-trick at Anfield, but I also remember a couple of games at Old Trafford, playing with Fernando Torres and Steven Gerrard.
"I can remember a late goal of mine in the FA Cup, so great memories and hopefully tomorrow will be another great day to remember."