The Red Devils went 12 points clear of crosstown rivals Manchester City with a 2-0 home win over the Toffees with Ferguson stating that he made alterations to his team, which takes on Real Madrid in the Champions League this week, after learning that City were beaten 3-1 by Southampton on Saturday.
"Yes I did. I thought I'd make seven changes but when the City result happened yesterday I thought it would be a more important game today for us because it gives us a comfortable lead," he told Sky Sports.
"We knew if we got a result today it would put us in a fantastic position. We can make changes later in the season."