The 22-year old, who trained with Arsenal last winter, has been capped 12 times by his country but all of those outings have been in international friendlies.
The US take on Jamaica in the first of two 2014 CONCACAF World Cup qualifiers on Friday, before the return bout next Tuesday, and Shea has his fingers crossed that manager Jurgen Klinsmann will give him the opportunity this time around.
"It doesn't matter who you're playing against, it's a World Cup qualifier and that's where you want to be," Shea told MLSsoccer.com.
"It's my first taste, so we'll see how it goes."
Shea came on as a second-half substitute to assist the winning goal scored by Michael Orozco as USA beat Mexico in a friendly earlier this month - their first win on Mexican soil in over three decades - and he feels that performance could help him again come off the bench this Friday.
"It feels good to play in a real game, hopefully, something that means something," he added.
"I don't really look at friendlies like a friendly anyways, but it would be good to get into a game that means something."