The Spanish champions return to Celtic Park, where they lost 2-1 last season, in the second group stage game of this campaign's Champions League.
Fabregas insists he and his Barca teammates will not be looking back to last season as they strive to deny the Glasgow clubs attacking aerial threat.
"We will not obsess about what happened last year," said the former Arsenal captain.
"We played a good game and what we need to do is keep possession, not give the ball away too easily, minimise our mistakes and maximise our chances.
"Set-pieces and counter-attacks will be the main threats from Celtic.
"If you follow European football you know that coming to Celtic Park is always going to be tough, wherever they are in the table or whichever manager they have.
"I played here with Arsenal and you have to expect a difficult game. The fans are always behind the team and that is pressure but I think we can deal with it.
"We have played in big games in our careers' and tomorrow will be one of them."
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