Former West Ham midfielder Frank Lampard hit out at the support after yesterday's defeat to Burnley.
Home fans invaded the pitch four times before turning their anger towards the directors box and to co-chairmen David Sullivan and fellow owner David Gold.
"It was very toxic today, a horrible feeling in the second half," Lampard said on Match of the Day.
"Fans confronting the players, I understand Mark Noble's position, he's Mr West Ham, he's a fan. This isn't right, whatever way you look at it.
"This was very aggressive today. I understand some of the fans' problem, they lost an identity moving stadium.
"The club have a £29million net spend since they've moved. It's not enough, they've gone backwards. So fans are asking the question - but not mid-game."