Everton will have the chance to emulate Merseyside rivals Liverpool and dump Standard Liege out of European competition, having drawn the Belgian outfit in the first round of the UEFA Cup.
Portsmouth go up against Portuguese side Vitoria SC, who are also known as Guimaraes.
Manchester City will face Cypriot side Omonia. Aston Villa are to play Bulgarian outfit Litex Lovech and Tottenham will be up against Polish club Wisla Krakow.