Everton's hopes of finishing fourth have been dealt a blow after Tim Cahill was ruled out for the rest of the season with a broken metatarsal.
Liverpool's defeat to Manchester United last weekend means Everton could go ahead of their nearest rivals with a victory at Anfield but Cahill's absence will be sorely felt.
The 28-year-old has struggled for fitness in the past month and managed just 10 minutes in the 1-1 draw with West Ham last weekend before being substituted.
Toffees boss David Moyes has accepted defeat in terms of the 10-goal midfielder featuring again this campaign.
"He has a broken foot and I wouldn't expect him to play again this season," said Moyes.
"It is disappointing but it happens. I think we can cope (with Cahill's absence)."