Fellaini goes into the game on the back of a two-goal display against Aston Villa.
"Every game against Manchester United is a good game. It's a big challenge but everyone wants to play Champions League so it is important to keep going and win every game."
Fellaini took his tally for the season to 10 league goals in the draw with Aston Villa at the weekend, a result he believes could turn out to be significant come the end of the season.
"It's difficult to win when you make a mistake but Everton have good spirit and try to win every game at home. It was a good point," he added.
"Every game I try to give my maximum and to score goals. It's not just me - the players and supporters help, everything is important."