There were narrow wins for Liverpool and Newcastle but Tottenham drew again in the competition leaving them fighting to progress in the Europa League. Tottenham are in increasing danger of failing to reach the knockout stages of the competition after being held to a lacklustre 1-1 draw against NK Maribor in Slovenia.
The home side went ahead against the run of play three minutes before half-time through Robert Beric.
Gylfi Sigurdsson equalised close to the hour but Spurs could not find a winner.
Bayer Leverkusen moved top of Group K on goal difference over Metalist after a crushing 4-0 win at Rapid Vienna.
Strikes from Philipp Wollscheid, Karim Bellarabi and a brace from Gonzalo Castro were sufficient.
Newcastle moved three points clear of Group D after a 1-0 home success over Club Bruges.
The scoreline was more comfortable than may suggest with Papiss Cisse twice having chances to extend the Magpies lead.
Gabriel Obertan scored the only goal of the game after the break.
Anzhi Makhachkala lost their 13 game unbeaten run as they went down to a 1-0 defeat at Liverpool who now top Group A.
Stewart Downing got the only goal of the game in the second half against the disappointing Russians with Samuel Eto'o having the visitor's best chance.
Panathinaikos drew 1-1 with Lazio in Group J courtesy of an injury time leveller from substitute Jose Toche.
The Italians were given the lead by an own goal from Giourkas Seitaridis and looked set to clinch the points until the Greek late show.
Inter Milan needed a late winner from Rodrigo Palacio in the 88th-minute to overcome Partizan Belgrade 1-0 at the San Siro.
Inter joint are now joint top of Group H on seven points with Rubin Kazan who had a 1-0 home success over Azerbaijan side Neftci in Russia.
Lyon maintained their unbeaten record in Group I with a 2-1 win over last year's beaten finalists Athletic Bilbao.
A Lisandro Lopez opener was cancelled out by Ibai Gomez before a late strike for Jimmy Briand claimed a win for the French outfit.
